ANT5

Corporate Profile

Company Data

Title ANT5 Co., Ltd.
Founded October 2020
Head office Hiraki 3-9-38-6, Ube, Yamaguchi, 755-0096, Japan
Representative Michiyasu Suzuki President and CEO
Service Development, manufacturing and sales of medical devices for patients with brain diseases
Capitalization 12.25 million yen

【The Origin of our company name】

Advanced Neuro Thermal 5S: 1.Surgeon, 2.Sensing, 3.Salvation, 4.System, 5.Solutions

Corporate philosophy and vision

【Corporate philosophy】

We hope to save the lives and suffering of patients with severe brain diseases with “advanced technology”.
As a first step toward this goal, we will launch our R & D with the following vision.

【Corporate Vision】

"To be the global standard in sensor and cooling technology for patients with serious brain disease by 2030."

Message from the Top

I am Michiyasu Suzuki, President and CEO of ANT5.
Our company is a venture company established at Yamaguchi University to commercialize innovative diagnostic and therapeutic methods for severe brain diseases.
There are many patients with severe brain diseases such as severe neurotrauma, severe stroke (subarachnoid hemorrhage, cerebral infarction, intracerebral hemorrhage), and status epilepticus. In fact, the number of patients admitted to ICUs in Japan alone is 26,300 per year, and is increasing year by year due to aging. A similar trend is seen in the world, with 82,000 patients admitted to ICUs per year in the United States and 131,000 patients admitted to ICUs per year in Europe.
Since regeneration and neogenesis of nerve cells in the brain are very rare, there is no better treatment than protecting the brain. Therefore, with scientific advances and technological innovations, the progress of treatment techniques in these fields has been remarkable. However, our proposed method of optimal brain cooling while simultaneously monitoring multiple brain functions is a completely new concept, and further advances in treatment techniques are expected in this field.
Utilizing the innovative research results centered around Yamaguchi University, we will commercialize innovative therapeutic technologies such as multimodal sensors, focal brain cooling (FBC), and control of the transient receptor potential (TRP) family of temperature-sensitive receptors, thereby saving the lives and suffering of patients with severe brain diseases.
We appreciate your support for our activities.

December 2020
ANT5 Co., Ltd.
President and CEO


【Brief Biography of President and CEO】

Michiyasu Suzuki, MD, PhD, CVD and Neurotrauma Researcher
-1979-1996
Dept Neurosurgery, Tohoku University School of Medicine,
-1987-1989
UC Irvine Research fellow, Dept Neuropathology, Dept Neurobiology,
-1996-2000
Assistant Professor, Iwate Medical University
-2000~2020
Prof, Dept Neurosurgery, Yamaguchi University Graduate School of Medicine
-2020~2022
Prof, Dept. Advanced Temperature Neurobiology, Yamaguchi University School of Medicine (Special Assignment)
-October 2020
Establishment of ANT5, President and CEO

Company History

【Research history】

-2010
Intraoperative study showed that selective cooling of epileptic focus suppressed EEG and cerebral blood flow.
-2013
Focal brain temperature is increased by abnormal epileptic EEG in a rat acute convulsion model
-2014
Confirmation that cortical hemoglobin concentration changes in response to fluctuations in brain temperature
-2018
Multimodal sensor-based brain activity monitoring in epilepsy patients shows significant changes in EEG, brain temperature, and cortical hemoglobin concentration during epileptic seizures
-2017-2020
Cortical spreading depolarizing EEG is also identified as changes in brain temperature and cortical hemoglobin concentration in bedside monitoring using multimodal sensors for stroke patients

【Background of the development】

-2010
Development of automatically deployable subdural electrode using shape memory alloy
-2011
Development of automatically deployable subdural electrodes using flexible printed circuit boards (FPCs)
-2012
FPC-based Thermistor & ECoG Probe and NIRS & ECoG probe using FPC
-2014
FPC for Intraoperative Monitoring Development of Multimodal Sensor Development
-2016
FPC-based intracranial implantable Multimodal Sensor Development
-2018
Development of an on-board multimodal sensor for brain pressure